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Is Ketamine Effective in Successful Treatment of PTSD

PTSD or post-traumatic stress disorder is one of the commonly occurring mental disorders in men and women. Ketamine is a potent drug that has successfully treated PTSD cases along with providing significant recovery from other mood disorders such as anxiety disorders, depression, suicidal tendencies, etc.

This drug started off as an anesthetic and was approved by the FDA, but later researchers proved its effectiveness in treating several acute health issues too. Let us see more about efficacy of ketamine on PTSD.

What is PTSD?

PTSD is a short form of post-traumatic stress disorder. It is an acute mental health disorder. This condition is caused due to a traumatic event that has happened in the life of the person. People who suffer from PTSD are haunted by this terrifying condition. They feel terrified and under trauma even when they are at a safe place.

People who go through this condition needs time to adjust and recover. This disorder adversely impacts personal and professional relationships of people. It is seen in the form of distressing memories, overwhelming guilt, recurrent nightmares, self-destructive behavior, emotional distress, etc.        

Mind Peace Clinic is one of the successful clinics in the treatment of a wide range of mental disorders. The clinic uses ketamine infused therapies that have significantly contributed to restoring the health of people to the best state.

What is the impact of ketamine on PTSD?

Today, a lot of people who face anxiety disorders are dealt with a generic antidepressant, like SSRI, an SNRI, or a benzodiazepine. These treatment procedures work on the levels of serotonin in the body to treat a mental health condition.

If these treatments fail to show the desired outcome, then other therapies are used such as cognitive behavioral therapy, or metallization-based therapy.

As in some cases, both these therapies do not lead to successful recovery in a person. Looking at this condition, researchers studied novel agents like ketamine. It was found that ketamine has been highly effective in the treatment of several anxiety disorders that includes post-traumatic stress disorder and social anxiety disorder.

Working of Ketamine in the treatment of PTSD

Glutamate is an important excitatory neurotransmitter that plays a role in mediating stress and dealing with traumatic memories of a person. Ketamine is a type of ionotropic glutamatergic N-methyl-d-aspartate receptor antagonist. It basically shows the anti-anxiety and antidepressant impact on people.

Ketamine enhances the secretion of brain-derived neurotrophic factor by inhibiting glycogen synthase kinase-3. Where a standard treatment requires six to twelve weeks in showing up noticeable results in mental disorder, ketamine medication can start to show results in just 24 hours of taking ketamine infusion therapy.


Ketamine for the treatment of depression has seen a powerful evidence base. It has rapidly grown its evidence base for successful use in treating anxiety disorders.

Looking at the gaps in present treatment, ketamine serves as a hopeful agent that delivers a more promising role in the cure of anxiety disorders like PTSD. Ketamine has the potential to bring a major difference in the life of countless people suffering from this devastating condition.

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